CRYAB anticorps

N° du produit ABIN7113086

L’anticorps Lapin Polyclonal anti-CRYAB a été validé pour WB, ELISA, IHC et IP. Il convient pour détecter CRYAB dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour CRYAB anticorps (ABIN7113086)

Antigène: CRYAB (Crystallin, alpha B (CRYAB))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYAB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-CRYAB anticorps

Fonction: CRYAB antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: crystallin, alpha B

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CRYAB

Antigène: CRYAB (Crystallin, alpha B (CRYAB))

Autre désignation: CRYAB

Sujet:

Synonyms: Alpha-crystallin B chain|Alpha(B)-crystallin|Heat shock protein beta-5 (HspB5)|Renal carcinoma antigen NY-REN-27|Rosenthal fiber component|CRYAB|CRYA2|HSPB5

Background: Alpha B-crystallin, encoded by CRYAB gene, is multifunctional, serving as both a major structural protein in the lens and a small heat-shock protein in other tissues in mammals. Alpha B-crystallin may contribute to the transparency and refractive index of the lens. Single nucleotide polymorphisms(SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. Mutations in the CRYAB gene cause distinct clinical phenotypes including isolated posterior polar cataract, myofibrillar myopathy, cardiomyopathy, or a multisystemic disorder combining all these features. Impairment of alpha-B crystallin dimerization may be relevant to the pathogenesis of these disorders.

Poids moléculaire: 20 kDa

UniProt: P02511